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Item number: Cay10009110-500

W140 is the inactive enantiomer of the sphingosine-1-phosphate receptor 1 (S1P1) antagonist W146 (Cay-10009109). It only weakly binds to S1P1 (Ki = 4.6 µM for the human receptor). W140 has been used as a negative control in vitro and in vivo in the study of S1P1 signaling.Formal Name:...

Keywords:	[3S-amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid, mono(trifluoroacetate)
Application:	S1P1 Antagonist Control
CAS	909725-64-0
MW:	456.4 D

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W140 (trifluoroacetate salt)

Item number: TGM-T38336-1mg

Description: Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1/EDG-1,...

Keywords:	W140 (trifluoroacetate salt)
Application:	S1P1 Antagonist Control
CAS	909725-64-0
MW:	456.399 D

From 265.00€ *

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