UBP 301

UBP 301 is an antagonist of the kainate receptor, an ionotropic glutamate receptor (apparent Kd = 5.94 µM). It displays ~30-fold selectivity over AMPA receptors. UBP 301 is used to assess the roles of kainate receptors in neuronal signaling, particularly in reference to neuropathic pain.Formal Name: (alphaS)-alpha-amino-3-[(4-carboxyphenyl)methyl]-3,4-dihydro-5-iodo-2,4-dioxo-1(2H)-pyrimidinepropanoic acid. CAS Number: 569371-10-4. Molecular Formula: C15H14IN3O6. Formula Weight: 459.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 0.5 mg/ml (w/ gentle warming). lambdamax: 230, 280 nm. SMILES: OC([C@@H](N)CN1C=C(I)C(N(CC2=CC=C(C(O)=O)C=C2)C1=O)=O)=O. InChi Code: InChI=1S/C15H14IN3O6/c16-10-6-18(7-11(17)14(23)24)15(25)19(12(10)20)5-8-1-3-9(4-2-8)13(21)22/h1-4,6,11H,5,7,17H2,(H,21,22)(H,23,24)/t11-/m0/s1. InChi Key: JHSYCOCOIYSZGI-NSHDSACASA-N.