34 products were found matching "K05201"!

Domoic acid is a kainate receptor agonist, neurotoxin, and an analog of (-)-(alpha)-kainic acid (Cay-78050). Domoic acid binds to GluR5, GluR6, and GluR7 recombinant homomeric kainate receptors (Kis = 2, 6, and 37 nM, respectively), KA-1 and KA-2 kainate receptors, and the GluR4 AMPA receptor. It also binds to...

Anti-Grik1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Grik1 from other sources has not been determined. Protein function: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous...

Anti-Grik1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Grik1 from other sources has not been determined. Protein function: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Glutamate receptor, ionotropic, kainate 1, also known as GLUR5, is a protein that in humans is encoded by the GRIK1 gene. It is mapped to 21q21.3. This gene encodes one of the many ionotropic glutamate receptor (GluR) subunits that function as a ligand-gated ion...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Glutamate receptor ionotropic kainate 1, GLuR5 Protein function: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system....

UBP 310 is an antagonist of ionotropic glutamate receptor 5 (GluR5 or GluK1, Kd = 130 nM). It less potently binds GluR2 (GluA2) and GluR6 (GluK2, Kds = 106 and 1,626 µM, respectively). UBP 310 is inactive at metabotropic GluR group I and NMDA receptors.Formal Name:...

Protein function: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical...

UBP 302 is an antagonist of glutamate receptor 5 (GluR5) subunit-containing kainate receptors that inhibits kainate-induced responses in isolated rat dorsal roots (Kd = 402 nM). In vitro, UBP 302 inhibits gamma frequency oscillations in the rat basolateral amygdala at a concentration of 25 µM, and blocks kainate...

Protein function: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical...

ATPA is an agonist of ionotropic glutamate receptor 5 (GluR5/GluK1, Ki = 0.0043 µM). It is selective for GluR5 over GluR1-4 (Kis = 6-14 µM), as well as GluR6 (Ki = >1,000 µM). ATPA induces inward currents in HEK293 cells expressing recombinant human GluR5 and isolated rat dorsal root ganglion (DRG) neurons (EC50s =...

Arcaine is an antagonist of the NMDA receptor (IC50 = 9.13 µM). It inhibits NMDA and glycine-induced inward currents in X. laevis oocytes expressing rat NMDA receptors with an IC50 value of 60.1 µM. Arcaine impairs contextual and auditory fear conditioning in rats when administered intraperitoneally post-training at...

Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...