Tolebrutinib
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay37723-5 | 5 mg | - |
6 - 10 business days* |
90.00€
|
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| Cay37723-10 | 10 mg | - |
6 - 10 business days* |
161.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Tolebrutinib is an irreversible inhibitor of Bruton's tyrosine kinase (BTK, IC50 = 1 nM). It... more
Product information "Tolebrutinib"
Tolebrutinib is an irreversible inhibitor of Bruton's tyrosine kinase (BTK, IC50 = 1 nM). It decreases the number of CD69+ B cells in isolated mouse whole blood (IC50 = 200 nM).Formal Name: 4-amino-1,3-dihydro-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-3-(4-phenoxyphenyl)-2H-imidazo[4,5-c]pyridin-2-one. CAS Number: 1971920-73-6. Molecular Formula: C26H25N5O3. Formula Weight: 455.5. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. lambdamax: 222 nm. SMILES: NC1=C2C(N([C@@]3([H])CN(CCC3)C(C=C)=O)C(N2C4=CC=C(C=C4)OC5=CC=CC=C5)=O)=CC=N1. InChi Code: InChI=1S/C26H25N5O3/c1-2-23(32)29-16-6-7-19(17-29)30-22-14-15-28-25(27)24(22)31(26(30)33)18-10-12-21(13-11-18)34-20-8-4-3-5-9-20/h2-5,8-15,19H,1,6-7,16-17H2,(H2,27,28)/t19-/m1/s1. InChi Key: KOEUOFPEZFUWRF-LJQANCHMSA-N.
| Keywords: | 4-amino-1,3-dihydro-1-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-3-(4-phenoxyphenyl)-2H-imidazo[4,5-c]pyridin-2-one |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 37723 |
Properties
| Application: | Irreversible BTK inhibitor |
| MW: | 455.5 D |
| Formula: | C26H25N5O3 |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 1971920-73-6| Matching products |
| KEGG ID : | K07370 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H315, H319, H335 |
| P Phrases: | P261, P264, P270, P271, P280, P312, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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