Shz-1

Shz-1 is a Shz that activates cardiac differentiation, inducing the expression of early cardiac genes in mouse pluripotent and embryonic stem cells in vitro at low micromolar concentrations. In addition, Shz-1 drives differentiation of human peripheral blood mononuclear cells, mobilized by granule colony-stimulating factor, toward a cardiac phenotype. These Shz-1 treated cells enhance myocardial regenerative repair in cryo-injured rat heart.Formal Name: benzenesulfonic acid, 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide. CAS Number: 326886-05-9. Synonyms: Sulfonylhydrazone-1. Molecular Formula: C13H11BrN2O3S. Formula Weight: 355.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, Ethanol: 30 mg/ml. lambdamax: 219, 275, 329 nm. SMILES: O=S(C1=CC=CC=C1)(N/N=C/C2=C(O)C=CC(Br)=C2)=O. InChi Code: InChI=1S/C13H11BrN2O3S/c14-11-6-7-13(17)10(8-11)9-15-16-20(18,19)12-4-2-1-3-5-12/h1-9,16-17H/b15-9+. InChi Key: OEMCLQLAWYKPRK-OQLLNIDSSA-N.