Selonsertib

Item number	Size	Manual	SDS	Delivery time	Price
SYN-1231-M001	1 mg	-	-	3 - 9 business days*	119.00€
SYN-1231-M005	5 mg	-	-	3 - 9 business days*	250.00€
SYN-1231-M010	10 mg	-	-	3 - 9 business days*	382.00€
SYN-1231-M050	50 mg	-	-	3 - 9 business days*	1,172.00€
SYN-1231-M100	100 mg	-	-	3 - 9 business days*	-

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Solid. Soluble in DMSO. Insoluble in water. Selonsertib, also known as GS-4997, is an orally... more

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Product information "Selonsertib"

Solid. Soluble in DMSO. Insoluble in water. Selonsertib, also known as GS-4997, is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities. GS-4997 targets and binds to the catalytic kinase domain of ASK1 in an ATP-competitive manner. GS-4997 prevents the production of inflammatory cytokines, down-regulates the expression of genes involved in fibrosis, suppresses excessive apoptosis and inhibits cellular proliferation.

Keywords:	GS-4997 (free base), 5-(4-Cyclopropyl-1H-imidazol-1-yl)-2-fluoro-N-(6-(4-isopropyl-4H-1,2,4-triazol-3-yl)pyridin-2-yl)-4-methylbenzamide
Supplier:	SYNkinase
Supplier-Nr:	1231

Properties

Application:	ASK1 inhibitor
MW:	445,5 D
Formula:	C24H24FN7O
Purity:	>95%
Format:	Solid

Database Information

CAS :	1448428-04-3\| Matching products
KEGG ID :	K04426 \| Matching products

Handling & Safety

Storage:	+4°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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