RG-13022

RG-13022
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10010309-5 5 mg -

6 - 10 business days*

58.00€
Cay10010309-10 10 mg -

6 - 10 business days*

109.00€
Cay10010309-50 50 mg -

6 - 10 business days*

460.00€
 
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases... more
Product information "RG-13022"
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block EGF-dependent cell proliferation. RG-13022 is an inhibitor of epidermal growth factor (EGF) receptor kinase with an IC50 value of 1 µM in HT-22 cells. Formal Name: alphaZ-[(3,4-dimethoxyphenyl)methylene]-3-pyridineacetonitrile. CAS Number: 149286-90-8. Molecular Formula: C16H14N2O2. Formula Weight: 266.3. Purity: >98%. Formulation: A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml, Ethanol: 2 mg/ml. lambdamax: 248, 356 nm. SMILES: N#C/C(=C\c1ccc(OC)c(OC)c1)/c1cccnc1. InChi Code: InChI=1S/C16H14N2O2/c1-19-15-6-5-12(9-16(15)20-2)8-14(10-17)13-4-3-7-18-11-13/h3-9,11H,1-2H3/b14-8+. InChi Key: DBGZNJVTHYFQJI-RIYZIHGNSA-N.
Keywords: alphaZ-[(3,4-dimethoxyphenyl)methylene]-3-pyridineacetonitrile
Supplier: Cayman Chemical
Supplier-Nr: 10010309

Properties

Application: EGF receptor kinase inhibitor
MW: 266.3 D
Formula: C16H14N2O2
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 149286-90-8| Find alternatives
KEGG ID : K04361 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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