Progesterone

Progesterone, along with pregnenolone, is the biosynthetic precursor of all other steroid hormones. Progesterone is synthesized from cholesterol by the sequential action of desmolase in the mitochondria, which produces pregnenolone, followed by Delta4,5-isomerase in the outer mitochondrial membrane and smooth endoplasmic reticulum of steroid-secreting cells. Progesterone activates the human progesterone receptor with an EC50 value of 0.5 nM.Formal Name: pregn-4-ene-3,20-dione. CAS Number: 57-83-0. Synonyms: Cyclogest, NSC 9704, NSC 64377. Molecular Formula: C21H30O2. Formula Weight: 314.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Acetonitrile: 1 mg/ml, Ethanol: 1 mg/ml, Methanol: 1 mg/ml. lambdamax: 239 nm. SMILES: C[C@@]12[C@](CC[C@@H]2C(C)=O)([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC1)=O. InChi Code: InChI=1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1. InChi Key: RJKFOVLPORLFTN-LEKSSAKUSA-N.