Piperlonguminine

Piperlonguminine is an alkaloid amide from species of the genus Piper, a plant used in traditional medicine that demonstrates antifungal, anticancer, antihyperlipidemic, and anti-inflammatory properties. Piperlonguminine (3-12.5 µM) has been shown to dose dependently decrease expression of amyloid precursor protein and amyloid-beta peptide in human neuroblastoma cells, suggesting it may have implication in treating Alzheimer's disease.Formal Name: 5-(1,3-benzodioxol-5-yl)-N-(2-methylpropyl)-2E,4E-pentadienamide. CAS Number: 5950-12-9. Synonyms: N-Isobutylpiperamide, NSC 125178. Molecular Formula: C16H19NO3. Formula Weight: 273.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2) (1:2): 5 mg/ml, Ethanol: 3 mg/ml, PBS (pH 7.2): Insolublwe. lambdamax: 242, 252, 308, 339 nm. SMILES: O=C(/C=C/C=C/C1=CC=C(OCO2)C2=C1)NCC(C)C. InChi Code: InChI=1S/C16H19NO3/c1-12(2)10-17-16(18)6-4-3-5-13-7-8-14-15(9-13)20-11-19-14/h3-9,12H,10-11H2,1-2H3,(H,17,18)/b5-3+,6-4+. InChi Key: WHAAPCGHVWVUEX-GGWOSOGESA-N.