PI4KIIIbeta Inhibitor 3

PI4KIIIbeta inhibitor 3 is an inhibitor of PI4KIIIbeta (IC50 = 19 nM). It is approximately 100-fold selective for PI4KIIIbeta over PI4KIIalpha, PI4KIIbeta, and PI4KIIIalpha, PI3Kalpha, PI3Kbeta, PI3Kgamma, and PI3Kdelta, and PI3KC3, as well as 100-500-fold selective over PI3KC2alpha, PI3KC2beta, and PI3KC2gamma.Formal Name: 4-[5-amino-2-(3-pyridinyl)thiazolo[5,4-d]pyrimidin-7-yl]-N -(4-methylphenyl)-1-piperazinecarboxamide. CAS Number: 1245319-54-3. Molecular Formula: C22H22N8OS. Formula Weight: 446.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble, Methanol: Soluble. SMILES: O=C(N1CCN(CC1)C2=C3N=C(C4=CN=CC=C4)SC3=NC(N)=N2)NC5=CC=C(C)C=C5. InChi Code: InChI=1S/C22H22N8OS/c1-14-4-6-16(7-5-14)25-22(31)30-11-9-29(10-12-30)18-17-20(28-21(23)27-18)32-19(26-17)15-3-2-8-24-13-15/h2-8,13H,9-12H2,1H3,(H,25,31)(H2,23,27,28). InChi Key: UWTRKIJAGTTXNM-UHFFFAOYSA-N.