PF-07304814

PF-07304814 is a prodrug form of the severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 main protease (Mpro), also known as 3C-like protease (3CLpro), inhibitor PF-00835231 (Cay-36047).Formal Name: 4-methoxy-N-[(1S)-3-methyl-1-[[[(1S)-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]-3-(phosphonooxy)propyl]amino]carbonyl]butyl]-1H-indole-2-carboxamide. CAS Number: 2468015-78-1. Synonyms: Lufotrelvir. Molecular Formula: C24H33N4O9P. Formula Weight: 552.5. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: Soluble. SMILES: COC1=C2C(NC(C(N[C@@H](CC(C)C)C(N[C@H](C(COP(O)(O)=O)=O)C[C@H]3C(NCC3)=O)=O)=O)=C2)=CC=C1. InChi Code: InChI=1S/C24H33N4O9P/c1-13(2)9-18(28-24(32)19-11-15-16(26-19)5-4-6-21(15)36-3)23(31)27-17(10-14-7-8-25-22(14)30)20(29)12-37-38(33,34)35/h4-6,11,13-14,17-18,26H,7-10,12H2,1-3H3,(H,25,30)(H,27,31)(H,28,32)(H2,33,34,35)/t14-,17-,18-/m0/s1. InChi Key: FQKALOFOWPDTED-WBAXXEDZSA-N.