14 products were found matching "K25015"!

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PF-07304814
PF-07304814

Item number: Cay37026-1

PF-07304814 is a prodrug form of the severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 main protease (Mpro), also known as 3C-like protease (3CLpro), inhibitor PF-00835231 (Cay-36047).Formal Name:...
Keywords: Lufotrelvir,...
Application: PF-00835231 prodrug form
CAS 2468015-78-1
MW: 552.5 D
From 34.00€ *
Review
Mca-AVLQSGFR-K(Dnp)-K-NH2 (trifluoroacetate salt)
Mca-AVLQSGFR-K(Dnp)-K-NH2 (trifluoroacetate salt)

Item number: Cay37002-1

Mca-AVLQSGFR-K(Dnp)-K-NH2 is a fluorogenic substrate for severe acute respiratory syndrome coronavirus (SARS-CoV) main protease (Mpro), also known as 3C-like protease (3CLpro). Upon cleavage by SARS-CoV Mpro, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify SARS-CoV Mpro...
Keywords: N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-alanyl-L-valyl-L-leucyl-L-glutaminyl-L-serylglycyl-L-phenylalanyl-L-a...
Application: Fluorogenic SARS-CoV Mpro substrate
MW: 1514.7 D
From 122.00€ *
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Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab (3235-3246)-E-EDANS (trifluoroacetate salt)
Dabcyl-K-SARS-CoV-2 Replicase Polyprotein 1ab...

Item number: Cay37409-1

Dabcyl-K-SARS-CoV-2 replicase polyprotein 1ab (pp1ab) (3235-3246)-E-EDANS is a fluorogenic substrate for severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 main protease (Mpro), also known as 3C-like protease (3CLpro). Upon enzymatic cleavage by SARS-CoV or SARS-CoV-2 Mpro at the Gln-Ser site,...
Keywords: Dabcyl-KTSAVLQSGFRKME-EDANS, Dabcyl-Lys-Thr-Ser-Ala-Val-Leu-Gln-Ser-Gly-Phe-Arg-Lys-Met-Glu-EDANS,...
Application: Fluorogenic SARS-CoV / SARS-CoV-2 Mpro substrate
MW: 2081.4 D
From 582.00€ *
Review
3CL Protease (T21I, S144A) (SARS-CoV-2) Recombinant
3CL Protease (T21I, S144A) (SARS-CoV-2) Recombinant

Item number: BPS-101669-1

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutations of interests (T21I) and (S144A) and is affinity purified.
Keywords: EC=3.4.22.-, EC=3.4.22.69, 3CL Protease (T21I, S144A) (1-306(end)) (SARS-CoV-2)
Application: Enzyme kinetics, inhibitor screening, selectivity profiling, protease assays
Expressed in: E.coli
Origin: SARS-CoV-2
MW: 34 kD
From 591.00€ *
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3CL Protease (T21I, E166V) (SARS-CoV-2) Recombinant
3CL Protease (T21I, E166V) (SARS-CoV-2) Recombinant

Item number: BPS-101671-1

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutations of interests (T21I) and (E166V) and is affinity purified.
Keywords: EC=3.4.22.-, EC=3.4.22.69, 3CL Protease (T21I, E166V) (1-306(end)) (SARS-CoV-2)
Application: Enzyme kinetics, inhibitor screening, selectivity profiling, protease assays
Expressed in: E.coli
Origin: SARS-CoV-2
MW: 34 kD
From 591.00€ *
Review
3CL Protease (T21I, A173V, T304I), (SARS-CoV-2) Recombinant
3CL Protease (T21I, A173V, T304I), (SARS-CoV-2) Recombinant

Item number: BPS-101679-1

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutations of interests (T21I), (A173V) and (T304I) and is affinity purified.
Keywords: EC=3.4.22.-, EC=3.4.22.69, 3CL Protease (T21I, A173V, T304I) (1-306(end)) (SARS-CoV-2)
Application: Enzyme kinetics, inhibitor screening, selectivity profiling, protease assays
Expressed in: E.coli
Origin: SARS-CoV-2
MW: 34 kD
From 591.00€ *
Review
3CL Protease (T21I, T304I) (SARS-CoV-2) Recombinant
3CL Protease (T21I, T304I) (SARS-CoV-2) Recombinant

Item number: BPS-101685-1

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutations of interests (T21I) and (T304I) and is affinity purified.
Keywords: EC=3.4.22.-, EC=3.4.22.69,
Application: Enzyme kinetics, inhibitor screening, selectivity profiling, protease assays
Expressed in: E.coli
Origin: SARS-CoV-2
MW: 34 kD
From 591.00€ *
Review
3CL Protease (P252L) (SARS-CoV-2) Recombinant
3CL Protease (P252L) (SARS-CoV-2) Recombinant

Item number: BPS-101692-1

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutation of interest (P252L) and is affinity purified.
Keywords: EC=3.4.22.-, EC=3.4.22.69,
Application: Enzyme kinetics, inhibitor screening, selectivity profiling, protease assays
Expressed in: E.coli
Origin: SARS-CoV-2
MW: 34 kD
From 591.00€ *
Review
COVID-19 Research
PF-07321332
PF-07321332

Item number: Cay35257-1

PF-07321332 is an orally bioavailable inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), with a Ki value of 3.11 nM. It also inhibits Mpro from other members of the Betacoronavirus genus, including SARS-CoV-1, HKU1-CoV, OC43-CoV,...
Keywords: Nirmatrelvir,...
Application: SARS-CoV-2 Mpro inhibitor
CAS 2628280-40-8
MW: 499.5 D
From 119.00€ *
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ML-188
ML-188

Item number: Cay37346-1

ML-188 is an inhibitor of severe acute respiratory coronavirus (SARS-CoV) main protease (Mpro), also known as 3C-like protease (3CLpro, IC50 = 1.5 µM).Formal Name: (alphaR)-N-(1,1-dimethylethyl)-alpha-[[4-(1,1-dimethylethyl)phenyl](2-furanylcarbonyl)amino]-3-pyridineacetamide. CAS Number: 1417700-13-0. Molecular...
Keywords: (alphaR)-N-(1,1-dimethylethyl)-alpha-[[4-(1,1-dimethylethyl)phenyl](2-furanylcarbonyl)amino]-3-pyridineacetamide
Application: SARS-CoV Mpro inhibitor
CAS 1417700-13-0
MW: 433.5 D
From 68.00€ *
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Ensitrelvir
Ensitrelvir

Item number: Cay37945-5

Ensitrelvir is an orally bioavailable inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), with an IC50 value of 0.013 µM. It is selective for Mpro over HIV-1 protease and the human proteases caspase-2, chymotrypsin, thrombin, and...
Keywords: S-217622,...
Application: SARS-CoV-2 Mpro inhibitor
CAS 2647530-73-0
MW: 531.9 D
From 48.00€ *
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PF-00835231
PF-00835231

Item number: Cay36047-1

PF-00835231 is an inhibitor of severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 main protease (Mpro), also known as 3C-like protease (3CLpro, Kis = 4 and 0.27 nM, respectively). It reduces the infectivity of SARS-CoV and common cold human coronavirus 229E (HCoV-229E) in Vero cells (EC50s = 4.8...
Keywords: N-[(1S)-1-[[[(1S)-3-hydroxy-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]propyl]amino]carbonyl]-3-methylbutyl]-4-methoxy-1H-...
Application: SARS-CoV / SARS-CoV-2 Mpro inhibitor
CAS 870153-29-0
MW: 472.5 D
From 76.00€ *
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