24 products were found matching "K25015"!

PF-07321332 is an orally bioavailable inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro), with a Ki value of 3.11 nM. It also inhibits Mpro from other members of the Betacoronavirus genus, including SARS-CoV-1, HKU1-CoV, OC43-CoV,...

Description: PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) . Target: SARS-CoV. Smiles: C(N[C@@H](C[C@H]1C(=O)NCC1)C#N)(=O)[C@@H]2[C@@]3([C@@](C3(C)C)(CN2C([C@@H](NC(C(F)(F)F)=O)[C@](C)(C)C)=O)[H])[H]. References: Li J, et al. Nirmatrelvir exerts distinct antiviral potency...

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutations of interests (T21I) and (S144A) and is affinity purified.

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutations of interests (T21I) and (E166V) and is affinity purified.

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutations of interests (T21I), (A173V) and (T304I) and is affinity purified.

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutations of interests (T21I) and (T304I) and is affinity purified.

Recombinant SARS-CoV-2 3C-like Protease, full length, encompassing amino acids 1-306(end). This construct does not contain a tag. The recombinant protein contains the mutation of interest (P252L) and is affinity purified.

Mca-AVLQSGFR-K(Dnp)-K-NH2 is a fluorogenic substrate for severe acute respiratory syndrome coronavirus (SARS-CoV) main protease (Mpro), also known as 3C-like protease (3CLpro). Upon cleavage by SARS-CoV Mpro, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify SARS-CoV Mpro...

Dabcyl-K-SARS-CoV-2 replicase polyprotein 1ab (pp1ab) (3235-3246)-E-EDANS is a fluorogenic substrate for severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 main protease (Mpro), also known as 3C-like protease (3CLpro). Upon enzymatic cleavage by SARS-CoV or SARS-CoV-2 Mpro at the Gln-Ser site,...

PF-07304814 is a prodrug form of the severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 main protease (Mpro), also known as 3C-like protease (3CLpro), inhibitor PF-00835231 (Cay-36047).Formal Name:...

rac-X77 is an inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro), also known as 3C-like protease (3CLpro, IC50 = 4.1 µM).Formal Name: N-cyclohexyl-alpha-[[4-(1,1-dimethylethyl)phenyl](1H-imidazol-5-ylcarbonyl)amino]-3-pyridineacetamide. CAS Number: 2144491-78-9. Molecular...

Description: Cinanserin hydrochloride (SQ 10643), a high-affinity antagonist of the 5-HT2 receptor (Ki: 41 nM), is also a 3C-like protease inhibitor of severe acute respiratory syndrome coronavirus. Target: 5-HT Receptor, Influenza Virus. Smiles: Cl.CN(C)CCCSc1ccccc1NC(=O)C=Cc1ccccc1. References: Chen L, et al....