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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay27130-500 | 500 µg | - |
6 - 10 business days* |
135.00€
|
|||
Cay27130-1 | 1 mg | - |
6 - 10 business days* |
258.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
PAR3 (1-6) amide is a synthetic hexapeptide that corresponds to amino acid residues 1-6 of the... more
Product information "PAR3 (1-6) amide (mouse) (trifluoroacetate salt)"
PAR3 (1-6) amide is a synthetic hexapeptide that corresponds to amino acid residues 1-6 of the amino terminal tethered ligand sequence of mouse proteinase-activated receptor 3 (PAR3) and residues 38-43 of the full-length sequence. PAR3 (1-6) amide activates PAR1 and PAR2, but not PAR3 or PAR4. It does not induce thrombin signaling in COS-7 cells expressing PAR3, PAR4, or both receptors at concentrations less than or equal to 500 µM, however, it does activate PAR1 and PAR2 in a cross-desensitization assay in Jurkat T cells when used at concentrations of 500 and 1,000 µM. PAR3 (1-6) increases calcium levels in Kirsten virus-transformed rat kidney (KNRK) cells expressing rat or human PAR2, with a higher potency for rat PAR2.Formal Name: L-seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide, trifluoroacetate salt. Synonyms: H-Ser-Phe-Asn-Gly-Gly-Pro-NH2, SFNGGP amide, SFNGGP-NH2, SFN-NH2. Molecular Formula: C25H36N8O8 . XCF3COOH. Formula Weight: 576.6. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Water: 1 mg/ml. SMILES: NC([C@@H]1CCCN1C(CNC(CNC([C@H](CC(N)=O)NC([C@@H](NC([C@H](CO)N[H])=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O. InChi Code: InChI=1S/C25H36N8O8.C2HF3O2/c26-15(13-34)23(39)31-16(9-14-5-2-1-3-6-14)25(41)32-17(10-19(27)35)24(40)30-11-20(36)29-12-21(37)33-8-4-7-18(33)22(28)38,3-2(4,5)1(6)7/h1-3,5-6,15-18,34H,4,7-13,26H2,(H2,27,35)(H2,28,38)(H,29,36)(H,30,40)(H,31,39)(H,32,41),(H,6,7)/t15-,16-,17-,18-,/m0./s1. InChi Key: ZQLFFELRKCHBKB-YPFLJBJZSA-N.
Keywords: | H-Ser-Phe-Asn-Gly-Gly-Pro-NH2, SFNGGP amide, SFNGGP-NH2, SFN-NH2, L-seryl-L-phenylalanyl-L-asparaginylglycylglycyl-L-prolinamide, trifluoroacetate salt |
Supplier: | Cayman Chemical |
Supplier-Nr: | 27130 |
Properties
Application: | PAR1 / PAR2 agonist |
MW: | 576.6 D |
Formula: | C25H36N8O8 . XCF3COOH |
Purity: | >95% |
Format: | Solid |
Database Information
KEGG ID : | K04234 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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