Oxamflatin

Oxamflatin is a potent inhibitor of histone deacetylases (IC50 = 15.7 nM). It has been shown to alter the expression of several genes whose products are involved in cell morphology, motility, apoptosis, and cell cycle control, reducing the proliferation of cancer cells.Formal Name: N-hydroxy-5-[3-[(phenylsulfonyl)amino]phenyl]-2E-penten-4-ynamide. CAS Number: 151720-43-3. Synonyms: Metacept 3. Molecular Formula: C17H14N2O4S. Formula Weight: 342.4. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7.2) (1:10): 0.1 mg/ml, DMSO: 5 mg/ml, DMSO:PBS (pH 7.2) (1:10): 0.1 mg/ml, Ethanol: 0.5 mg/ml. lambdamax: 241, 296 nm. SMILES: O=S(NC1=CC(C#C/C=C/C(NO)=O)=CC=C1)(C2=CC=CC=C2)=O. InChi Code: InChI=1S/C17H14N2O4S/c20-17(18-21)12-5-4-7-14-8-6-9-15(13-14)19-24(22,23)16-10-2-1-3-11-16/h1-3,5-6,8-13,19,21H,(H,18,20)/b12-5+. InChi Key: QRPSQQUYPMFERG-LFYBBSHMSA-N.