Momelotinib

Item number	Size	Manual	Delivery time	Price
SYN-1035-M001	1 mg	-	3 - 9 business days*	106.00€
SYN-1035-M005	5 mg	-	3 - 9 business days*	154.00€
SYN-1035-M010	10 mg	-	3 - 9 business days*	211.00€
SYN-1035-M050	50 mg	-	3 - 9 business days*	593.00€
SYN-1035-M100	100 mg	-	3 - 9 business days*	-

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Soluble in DMSO. CYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F... more

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Product information "Momelotinib"

Soluble in DMSO. CYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F mutant . Using ATP kinase assays IC(50) values for JAK1 (11nm), JAK2, (18nM), JAK2, JAK2V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC(50) < 100nM) detected against CDK2/cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKCµ), ROCK2, and TBK1 kinase as well. Target: JAK2 , Kinase Group: PTK , Substrate: Tyrosine

Keywords:	CYT387, Momelotinib
Supplier:	SYNkinase
Supplier-Nr:	1035

Properties

Application:	JAK1 / JAK2 inhibitor
MW:	414,5 D
Formula:	C23H22N6O2
Purity:	>95%
Format:	Solid

Database Information

CAS :	1056634-68-4\| Matching products
KEGG ID :	K11217 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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