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MDL 72527 is a polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase (IC50s = 6.1 and 0.02 µM, respectively). It does not inhibit monoamine oxidase or D-amino acid oxidase. MDL 72527 inhibits PAO-dependent H2O2 production in vitro and in vivo and is used to study the role of PAO activity in diverse models, including infection, cancer, and hyperoxia.Formal Name: N1,N4-di-2,3-butadien-1-yl-1,4-butanediamine, dihydrochloride. CAS Number: 93565-01-6. Molecular Formula: C12H20N2 . 2HCl. Formula Weight: 265.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: slightly, DMSO: 0.33 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: C=C=CCNCCCCNCC=C=C. InChi Code: InChI=1S/C12H20N2/c1-3-5-9-13-11-7-8-12-14-10-6-4-2/h5-6,13-14H,1-2,7-12H2. InChi Key: IKSQCMLJDHRWOA-UHFFFAOYSA-N.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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