Isorhamnetin

Isorhamnetin is a natural flavonol aglycone that is the 3-methyl metabolite of quercetin (Cay-10005169). It has antioxidant activity and inhibits xanthine oxidase (IC50 = 0.40 µM). Isorhamnetin also competitively inhibits the human multidrug and toxic compounds extrusion transporter 1 (Ki = 0.32 µM), which has an important role in the excretion of xenobiotics at the kidney and liver. It has also been reported to potentiate the neurological actions of nerve growth factor, diminish the cardiotoxic impact of doxorubicin, and have beneficial anti-cancer effects.Formal Name: 3,5,7-trihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one. CAS Number: 480-19-3. Synonyms: 3'-O-methyl Quercetin. Molecular Formula: C16H12O7. Formula Weight: 316.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 204, 255, 367 nm. SMILES: OC(C=C1O)=CC2=C1C(C(O)=C(C3=CC=C(O)C(OC)=C3)O2)=O. InChi Code: InChI=1S/C16H12O7/c1-22-11-4-7(2-3-9(11)18)16-15(21)14(20)13-10(19)5-8(17)6-12(13)23-16/h2-6,17-19,21H,1H3. InChi Key: IZQSVPBOUDKVDZ-UHFFFAOYSA-N.