Eupatilin

Pale yellow powder. Soluble in DMSO, hot methanol or mixture of methanol and chloroform. Selective inhibitor of 5-lipoxygenase, Apoptosis and cell cycle arrest inducer, Anticancer compound, Inhibits ERK1/2, JNK, and NF-kappaB activation and expression of Raf-1 and Ras, Anti-proliferative compound, Anti-inflammatory and immunosuppressive, Anti-apoptotic compound in hepatocytes, Antioxidant, Antidiabetic. Enhances hepatic and plasma glucose metabolism and increases insulin secretion in type 2 diabetic mice, Inhibits angiogenesis by blocking STAT3 and VEGF expression, Neuroprotective, PI3K Class I, MKK3/6 and MKK4 inhibitor.