Edaglitazone

Edaglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It activates PPARgamma in a reporter assay using CV-1 cells expressing murine PPARgamma2 when used at concentrations ranging from 0.1 to 1 µM. Edaglitazone (1, 5, and 25 µM) increases [3H]2-deoxyglucose transport in the presence and absence of insulin and increases glycogen synthesis in the presence of insulin in soleus muscle strips isolated from obese rats.Formal Name: 5-[[4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione. CAS Number: 213411-83-7. Synonyms: BM 13.1258. Molecular Formula: C24H20N2O4S2. Formula Weight: 464.6. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 30 mg/ml. lambdamax: 218, 271 nm. SMILES: CC(OC(C1=CC=CC=C1)=N2)=C2CCOC3=C4C(SC=C4)=C(CC5SC(NC5=O)=O)C=C3. InChi Code: InChI=1S/C24H20N2O4S2/c1-14-18(25-23(30-14)15-5-3-2-4-6-15)9-11-29-19-8-7-16(21-17(19)10-12-31-21)13-20-22(27)26-24(28)32-20/h2-8,10,12,20H,9,11,13H2,1H3,(H,26,27,28). InChi Key: HAAXAFNSRADSMK-UHFFFAOYSA-N.