This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Diquafosol is an agonist of purinergic P2Y2 and P2Y4 receptors (EC50s = 0.1 and 0.4 µM, respectively, in calcium mobilization assays). It is selective for P2Y2 and P2Y4 receptors over P2Y6 receptors (EC50 = 20 µM). Ocular application of diquafosol (0.1 and 1% w/v) induces the release of mucin-like glycoproteins from rabbit conjunctival goblet cells, as well as reduces desiccation-induced corneal damage in a rabbit model of dry eye disease. Formulations containing diquafosol have been used in the treatment of dry eye disease.Formal Name: uridine 5'-(pentahydrogen tetraphosphate), P'''->5'-ester with uridine, tetrasodium salt. CAS Number: 211427-08-6. Synonyms: INS365, KPY 998. Molecular Formula: C18H22N4O23P4 . 4Na. Formula Weight: 878.2. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 263 nm. SMILES: O=P(OC[C@H]1O[C@@](N2C=CC(NC2=O)=O)([C@@H]([C@@H]1O)O)[H])([O-])OP(OP(OP(OC[C@@H]3[C@@H](O)[C@@H](O)[C@@](N4C(NC(C=C4)=O)=O)([H])O3)([O-])=O)([O-])=O)([O-])=O.[Na+].[Na+].[Na+].[Na+]. InChi Code: InChI=1S/C18H26N4O23P4.4Na/c23-9-1-3-21(17(29)19-9)15-13(27)11(25)7(41-15)5-39-46(31,32)43-48(35,36)45-49(37,38)44-47(33,34)40-6-8-12(26)14(28)16(42-8)22-4-2-10(24)20-18(22)30,,,,/h1-4,7-8,11-16,25-28H,5-6H2,(H,31,32)(H,33,34)(H,35,36)(H,37,38)(H,19,23,29)(H,20,24,30),,,,/q,4*+1/p-4/t7-,8-,11-,12-,13-,14-,15-,16-,,,,/m1..../s1. InChi Key: OWTGMPPCCUSXIP-FNXFGIETSA-J.
Keywords:
INS365, KPY 998, uridine 5'-(pentahydrogen tetraphosphate), P'''->5'-ester with uridine, tetrasodium salt
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
More information