D-Saccharic Acid 1,4-lactone (hydrate)

D-Saccharic acid 1,4-lactone is an inhibitor of beta-glucuronidase (IC50 = 45 µM for the human enzyme). It is commonly used as a standard in the development of novel inhibitors of beta-glucuronidase. D-Saccharic acid 1,4-lactone is also used to prevent the cleavage of glucuronides in plasma, serum, or urine by beta-glucuronidase in samples.Formal Name: 1,4-lactone D-glucaric acid, monohydrate. CAS Number: 61278-30-6. Synonyms: D-Glucaro-1,4-lactone. Molecular Formula: C6H8O7 . H2O. Formula Weight: 210.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 20 mg/ml, PBS (pH 7.2): 10 mg/ml. lambdamax: 216 nm. SMILES: O=C1O[C@@]([C@H](O)C(O)=O)([H])[C@H](O)[C@H]1O.O. InChi Code: InChI=1S/C6H8O7.H2O/c7-1-2(8)6(12)13-4(1)3(9)5(10)11,/h1-4,7-9H,(H,10,11),1H2/t1-,2-,3+,4+,/m1./s1. InChi Key: NPFKVZHSFSFLPU-QGBSHYGGSA-N.