Description: D-Saccharic acid 1,4-lactone hydrate is a potent beta-glucuronidase inhibitor (IC50=48.4 µM) that possesses anticarcinogenic, detoxifying, and antioxidant properties[1][2]. Target: Others. Smiles: O.O[C@@H]([C@H]1OC(=O)[C@H](O)[C@H]1O)C(O)=O. References: Taha M, et al. Synthesis, beta-glucuronidase...

D-Saccharic acid 1,4-lactone is an inhibitor of beta-glucuronidase (IC50 = 45 µM for the human enzyme). It is commonly used as a standard in the development of novel inhibitors of beta-glucuronidase. D-Saccharic acid 1,4-lactone is also used to prevent the cleavage of glucuronides in plasma, serum, or urine by...