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CL 316,243 is a beta3-adrenoceptor agonist (EC50 = 3 nM) that is >10,000-fold selective over beta1 and beta2. It causes a rapid decrease in blood glucose level in mice and has been used to study the induction of brown adipocytes and to increase thermogenesis in a mouse model of dietary obesity.Formal Name: 5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylic acid, disodium salt. CAS Number: 138908-40-4. Molecular Formula: C20H18ClNO7 . 2Na. Formula Weight: 465.8. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 0.5 mg/ml, PBS (pH 7.2): 3 mg/ml. lambdamax: 285 nm. SMILES: ClC1=CC=CC([C@@H](O)CN[C@H](C)CC2=CC=C(OC(C([O-])=O)(C([O-])=O)O3)C3=C2)=C1.[Na+].[Na+]. InChi Code: InChI=1S/C20H20ClNO7.2Na/c1-11(22-10-15(23)13-3-2-4-14(21)9-13)7-12-5-6-16-17(8-12)29-20(28-16,18(24)25)19(26)27,,/h2-6,8-9,11,15,22-23H,7,10H2,1H3,(H,24,25)(H,26,27),,/q,2*+1/p-2/t11-,15+,,/m1../s1. InChi Key: FUZBPOHHSBDTJQ-CFOQQKEYSA-L.
Keywords:
5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2,2-dicarboxylic acid, disodium salt
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