CCT244747
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Solid. Soluble in DMSO. CCT244747 is a novel, potent, highly selective, orally active, ATP... more
Product information "CCT244747"
Solid. Soluble in DMSO. CCT244747 is a novel, potent, highly selective, orally active, ATP competitive CHK1 inhibitor. CCT244747 can inhibit cellular CHK1 activity with an IC50 of 29-170nM. In multiple tumour cell models, this has the effect of significantly enhancing the cytotoxicity of several anticancer drugs (such as gemcitabine and irinotecan) and abrogating drug-induced S and G2 arrest.
| Keywords: | (R)-3-((1-(Dimethylamino)propan-2-yl)oxy)-5-((4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl)amino)pyrazine-2-carbonitrile |
| Supplier: | SYNkinase |
| Supplier-Nr: | 1216 |
Properties
| Application: | Potent, highly selective CHK1 inhibitor |
| MW: | 408,5 D |
| Formula: | C20H24N8O2 |
| Purity: | >95% |
| Format: | Solid |
Database Information
| CAS : | 1404095-34-6| Matching products |
| KEGG ID : | K02216 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +20°C (International: +20°C) |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H317, H332 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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