CAY10727

CAY10727 is an inhibitor of protein arginine deiminase 3 (PAD3, kinact/KI = 15,600 M-1min-1). It is selective for PAD3 over PAD1, -2, and -4 (kinact/KIs = 360, 1,110, and 1,460 M-1min-1, respectively).Formal Name: 2-chloro-N-[3-[1-[(2'-chloro[1,1'-biphenyl]-3-yl)methyl]-2,5-dioxo-4-imidazolidinyl]propyl]-ethanimidamide. CAS Number: 1671088-84-8. Molecular Formula: C21H22Cl2N4O2. Formula Weight: 433.3. Purity: >90%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 10 mg/ml. SMILES: ClC1=CC=CC=C1C2=CC=CC(CN3C(NC(CCCNC(CCl)=N)C3=O)=O)=C2. InChi Code: InChI=1S/C21H22Cl2N4O2/c22-12-19(24)25-10-4-9-18-20(28)27(21(29)26-18)13-14-5-3-6-15(11-14)16-7-1-2-8-17(16)23/h1-3,5-8,11,18H,4,9-10,12-13H2,(H2,24,25)(H,26,29). InChi Key: WBAMTPWAOJULCC-UHFFFAOYSA-N.