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Soluble in DMSO or ethanol. BMS387032 is a novel cyclin-dependent kinase inhibitor, which exhibits potent and selective inhibitory activity against Cdk2, Cdk7, and Cdk9. It inhibits CDK2 with an IC(50) of 48nM and up to 20-fold selective over CDK1/CDK4. It also inhibits CDK7/9 with IC(50) values of 62nM and 4nM. It has little effect on CDK6. Target: CDK2 - CDK7 - CDK9 , Kinase Group: CMGC , Substrate: Serine-Threonine
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