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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Bacopaside I is a saponin that has been found in B. monniera and has diverse biological... more
Product information "Bacopaside I"
Bacopaside I is a saponin that has been found in B. monniera and has diverse biological activities. It inhibits monoamine oxidase A (MAO-A) and MAO-B (IC50s = 17.08 and 94.22 µg/ml, respectively). Bacopaside I (5, 15, and 50 mg/kg) decreases immobility time in the tail suspension and forced swim tests, as well as brain malondialdehyde (MDA) levels, and increases brain superoxide dismutase (SOD) and glutathione peroxidase (GPX) activities in mice. It increases time spent in the target quadrant in the Morris water maze and reduces amyloid plaque formation in the APP/PS1 transgenic mouse model of Alzheimer's disease. Bacopaside I (3, 10, and 30 mg/kg) reduces cerebral edema and infarct volume in a rat model of transient focal ischemia induced by middle cerebral artery occlusion.Formal Name: (1S,2R,4aR,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-hexadecahydro-1-hydroxy-1,6b,9,9,12a-pentamethyl-2-(2-methyl-1-propen-1-yl)-4a,6a-methano-1H,6H-phenanthro[2,1-d]pyrano[2,3-b]pyran-10-yl O-alpha-L-arabinofuranosyl-(1->2)-O-[6-O-sulfo-beta-D-glucopyranosyl-(1->3)]-alpha-L-arabinopyranoside. CAS Number: 382148-47-2. Molecular Formula: C46H74O20S. Formula Weight: 979.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Methanol: soluble. SMILES: C[C@]12[C@@]34[C@@](CC[C@]1([H])[C@@]5([C@@](C(C)([C@H](CC5)O[C@H]6[C@@H]([C@H]([C@H](CO6)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)COS(=O)(O)=O)O[C@@H]8O[C@H]([C@@H]([C@H]8O)O)CO)C)([H])CC2)C)([H])[C@]9([H])[C@@](OC4)(OC[C@H]([C@@]9(O)C)/C=C(C)\C)C3. InChi Code: InChI=1S/C46H74O20S/c1-21(2)14-22-16-59-46-19-45(20-60-46)23(37(46)44(22,7)54)8-9-28-42(5)12-11-29(41(3,4)27(42)10-13-43(28,45)6)64-40-36(66-38-33(52)30(49)25(15-47)62-38)35(24(48)17-58-40)65-39-34(53)32(51)31(50)26(63-39)18-61-67(55,56)57/h14,22-40,47-54H,8-13,15-20H2,1-7H3,(H,55,56,57)/t22-,23-,24+,25+,26-,27+,28-,29+,30+,31-,32+,33-,34-,35+,36-,37+,38+,39+,40+,42+,43-,44+,45+,46-/m1/s1. InChi Key: SKFWOYHZBNAJGA-YAOMZRCFSA-N. Origin: Plant/Bacopa monnieri (L.) Wettst..
Keywords: | (1S,2R,4aR,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-hexadecahydro-1-hydroxy-1,6b,9,9,12a-pentamethyl-2-(2-methyl-1-propen-1-yl)-4a,6a-methano-1H,6H-phenanthro[2,1-d]pyrano[2,3-b]pyran-10-yl O-alpha-L-arabinofuranosyl-(1->2)-O-[6-O-sulfo-beta-D-glucopyranosyl- |
Supplier: | Cayman Chemical |
Supplier-Nr: | 11821 |
Properties
Application: | Bioactive saponin |
MW: | 979.1 D |
Formula: | C46H74O20S |
Purity: | >95% |
Format: | Solid |
Database Information
CAS : | 382148-47-2| Matching products |
KEGG ID : | K00274 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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