AZD-26

Item number	Size	Manual	Delivery time	Price
SYN-1160-M001	1 mg	-	3 - 9 business days*	256.00€
SYN-1160-M005	5 mg	-	3 - 9 business days*	507.00€
SYN-1160-M010	10 mg	-	3 - 9 business days*	796.00€
SYN-1160-M050	50 mg	-	3 - 9 business days*	-
SYN-1160-M100	100 mg	-	3 - 9 business days*	-

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Soluble in DMSO or ethanol. AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of... more

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Product information "AZD-26"

Soluble in DMSO or ethanol. AZD-26 is an inhibitor of AKT. AZD-26 inhibits the phosphorylation of Thr308 on AKT in BT474 cells with an IC(50) of 422nM. It also inhibits the phosphorylation of Ser473 on AKT in MDAMB468 cells with an IC(50) of 322nM. AZD-26 inhibited AKT mediated phosphorylation at ranges form 0.01µM to 10µM after 24 hour exposure in several rat and human cell models. Likewise AZD-25 used at 100-200mg/kg also inhibited AKT phosphorylation and subsequent activation. Target: AKT , Kinase Group: AGC , Substrate: Serine-Threonine

Keywords:	AZD26
Supplier:	SYNkinase
Supplier-Nr:	1160

Properties

Application:	AKT inhibitor
MW:	343,4 D
Formula:	C22H21N3O
Purity:	>95%
Format:	Solid

Database Information

CAS :	1357158-81-6\| Matching products
KEGG ID :	K04456 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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