4alpha-Phorbol 12,13-didecanoate

4alpha-Phorbol 12,13-didecanoate is a negative control for phorbol esters, phorbol 12-myristate 13-acetate (PMA, Cay-10008014) and phorbol 12,13-didecanoate (PDD). Though inactive for signaling through PKC, 4alpha-phorbol 12,13-didecanoate has been shown to activate transient receptor potential vanilloid 4 (TRPV4) channels.Formal Name: decanoic acid, 1,1'-[(1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl] ester. CAS Number: 27536-56-7. Synonyms: 4alpha-PDD, 4alpha-Phorbol 12,13-dicaprinate. Molecular Formula: C40H64O8. Formula Weight: 672.9. Purity: >99%. Formulation: (Request formulation change), A film. Solubility: DMSO: Soluble, Ethanol: Soluble. SMILES: CC(C1=O)=C[C@]2([H])[C@@]1(O)CC(CO)=C[C@]3([H])[C@]2(O)[C@H](C)[C@@H](OC(CCCCCCCCC)=O)[C@]4(OC(CCCCCCCCC)=O)[C@H]3C4(C)C. InChi Code: InChI=1S/C40H64O8/c1-7-9-11-13-15-17-19-21-32(42)47-36-28(4)39(46)30(24-29(26-41)25-38(45)31(39)23-27(3)35(38)44)34-37(5,6)40(34,36)48-33(43)22-20-18-16-14-12-10-8-2/h23-24,28,30-31,34,36,41,45-46H,7-22,25-26H2,1-6H3/t28-,30+,31-,34-,36-,38+,39-,40-/. InChi Key: DGOSGFYDFDYMCW-OEFRVDPMSA-N.