Mouse GDF5 (Growth Differentiation Factor 5) CLIA Kit
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-MOES00317.96 | 96 assays | - |
9 - 20 business days* |
694.00€
|
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You can also order by e-mail: info@biomol.com
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
ELISA Type: CLIA. Sensitivity: 18.75 ng/mL. Range: 31.25--2000 ng/mL. Protein function: Growth... more
Product information "Mouse GDF5 (Growth Differentiation Factor 5) CLIA Kit"
ELISA Type: CLIA. Sensitivity: 18.75 ng/mL. Range: 31.25--2000 ng/mL. Protein function: Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction. Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG. Required to prevent excessive muscle loss upon denervation. This function requires SMAD4 and is mediated by phosphorylated SMAD1/5/8 (PubMed:24076600). Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes. [The UniProt Consortium]
| Keywords: | Gdf5, Bmp14, GDF-5, BMP-14, Bone morphogenetic protein 14, Growth/differentiation factor 5 |
| Supplier: | Assay Genie |
| Supplier-Nr: | MOES00317 |
Properties
| Application: | CLIA |
| Species reactivity: | mouse |
| Format: | Solid Phase |
Database Information
| KEGG ID : | K04664 | Matching products |
| UniProt ID : | P43027 | Matching products |
| Gene ID | GeneID 14563 | Matching products |
Handling & Safety
| Storage: | vT |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319 |
| P Phrases: | P264, P280 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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