LIMK1/2 (Phospho-Thr505) Colorimetric Cell-Based ELISA Kit

Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CBCAB01561.96 96 assays (2 x 96-well microplates) - -

9 - 20 business days*

641.00€
 
LIMK1/2 (Phospho-Thr505) Colorimetric Cell-Based ELISA Kit Protein function:... more
Product information "LIMK1/2 (Phospho-Thr505) Colorimetric Cell-Based ELISA Kit"
LIMK1/2 (Phospho-Thr505) Colorimetric Cell-Based ELISA Kit Protein function: Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PubMed:10436159, PubMed:11018042). Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159, PubMed:11018042). Involved in astral microtubule organization and mitotic spindle orientation during early stages of mitosis by mediating phosphorylation of TPPP (PubMed:22328514). Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro (PubMed:8537403). Suppresses ciliogenesis via multiple pathways, phosphorylation of CFL1, suppression of directional trafficking of ciliary vesicles to the ciliary base, and by facilitating YAP1 nuclear localization where it acts as a transcriptional corepressor of the TEAD4 target genes AURKA and PLK1 (PubMed:25849865). [The UniProt Consortium]
Keywords: LIMK2, LIMK-2, LIM domain kinase 2
Supplier: Assay Genie
Supplier-Nr: CBCAB01561

Properties

Application: In-cell ELISA

Database Information

KEGG ID : K05744 | Matching products
UniProt ID : P53671 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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