Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| BPS-78852 | 96 rxns | - | - |
3 - 15 business days* |
1,753.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The WRN Helicase Activity Assay is a fluorogenic assay designed for screening and profiling of... more
Product information "WRN Helicase Activity Assay Kit"
The WRN Helicase Activity Assay is a fluorogenic assay designed for screening and profiling of WRN (Werner Syndrome ATP-dependent Helicase) antagonists/inhibitors by monitoring their effect on WRN-catalyzed DNA unwinding. WRN inhibitor NCGC00063279 is also included as a control. The DNA probe is conjugated on one strand with the TAMRA (tetramethylrhodamine) fluorophore, and on the other strand with BHQ (Black Hole Quencher) which effectively quenches TAMRA fluorescence due to their proximity within the DNA double strand. WRN unwinding of the DNA probe separates the two strands, releasing TAMRA fluorescence. WRN activity, therefore, results in a proportional increase in fluorescence.
| Keywords: | WRN, RECQ3, 3'-5' exonuclease, RecQ protein-like 2, ATP-dependent helicase, Werner syndrome protein, DNA helicase, RecQ-like type 3, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, |
| Supplier: | BPS Bioscience |
| Supplier-Nr: | 78852 |
Properties
| Application: | Small molecule inhibitor / antagonist screening, HTS |
| Species reactivity: | human |
| Format: | Homog. |
Database Information
| KEGG ID : | K10900 | Matching products |
| UniProt ID : | Q14191 | Matching products |
| Gene ID | GeneID 7486 | Matching products |
Handling & Safety
| Storage: | -80°C |
| Shipping: | -80°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed