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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
BPS-78852 | 96 rxns | - | - |
3 - 15 business days* |
1,753.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
The WRN Helicase Activity Assay is a fluorogenic assay designed for screening and profiling of... more
Product information "WRN Helicase Activity Assay Kit"
The WRN Helicase Activity Assay is a fluorogenic assay designed for screening and profiling of WRN (Werner Syndrome ATP-dependent Helicase) antagonists/inhibitors by monitoring their effect on WRN-catalyzed DNA unwinding. WRN inhibitor NCGC00063279 is also included as a control. The DNA probe is conjugated on one strand with the TAMRA (tetramethylrhodamine) fluorophore, and on the other strand with BHQ (Black Hole Quencher) which effectively quenches TAMRA fluorescence due to their proximity within the DNA double strand. WRN unwinding of the DNA probe separates the two strands, releasing TAMRA fluorescence. WRN activity, therefore, results in a proportional increase in fluorescence.
Keywords: | WRN, RECQ3, 3'-5' exonuclease, RecQ protein-like 2, ATP-dependent helicase, Werner syndrome protein, DNA helicase, RecQ-like type 3, Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN, |
Supplier: | BPS Bioscience |
Supplier-Nr: | 78852 |
Properties
Application: | Small molecule inhibitor / antagonist screening, HTS |
Species reactivity: | human |
Format: | Homog. |
Database Information
KEGG ID : | K10900 | Matching products |
UniProt ID : | Q14191 | Matching products |
Gene ID | GeneID 7486 | Matching products |
Handling & Safety
Storage: | -80°C |
Shipping: | -80°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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