Anti-phospho-Tlk1 (Ser695) (Tousled-like kinase)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
600-401-469	100 µg		-	-	6 - 10 business days*		719.00€

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Protein function: Rapidly and transiently inhibited by phosphorylation following the generation... more

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Product information "Anti-phospho-Tlk1 (Ser695) (Tousled-like kinase)"

Protein function: Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S- phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin. Isoform 3 protects the cells from the ionizing radiation by faciliting the repair of DSBs. In vitro, phosphorylates histone H3 at 'Ser-10'. [The UniProt Consortium]

Keywords:	Anti-TLK1, Anti-KIAA0137, Anti-PKU-beta, EC=2.7.11.1, Anti-Tousled-like kinase 1, Anti-Serine/threonine-protein kinase tousled-like 1
Supplier:	Rockland Immunochemicals
Supplier-Nr:	600-401-469

Properties

Application:	ELISA, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	synthetic peptide corresponding to amino acids 737-751 of human Tlk1 (Tousled-like kinase) protein
Format:	Affinity Purified