Anti-phospho-STAT2 (Tyr690)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG51823.50	50 µl		-	-	6 - 14 business days*		436.00€
ARG51823.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Signal transducer and activator of transcription that mediates signaling by... more

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Product information "Anti-phospho-STAT2 (Tyr690)"

Protein function: Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [The UniProt Consortium]

Keywords:	Anti-phospho-p113, Anti-phospho-STAT2, Anti-phospho-Signal transducer and activator of transcription 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG51823

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Peptide sequence around phosphorylation site of tyrosine 690 (R-K-Y(p)-L-K)derived from Human Stat2
Format:	Liquid