Anti-phospho-PDCD4 (Ser457), clone 2E10.C12.H12

Anti-phospho-PDCD4 (Ser457), clone 2E10.C12.H12
Item number Size Datasheet Manual SDS Delivery time Quantity Price
200-301-B17 1 mg - -

3 - 9 business days*

3,096.00€
 
Protein function: Inhibits translation initiation and cap-dependent translation. May excert its... more
Product information "Anti-phospho-PDCD4 (Ser457), clone 2E10.C12.H12"
Protein function: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA. [The UniProt Consortium]
Keywords: Anti-phospho-H731, Anti-phospho-PDCD4, Anti-phospho-Protein 197/15a, Anti-phospho-Nuclear antigen H731-like, Anti-phospho-Programmed cell death protein 4, Anti-phospho-Neoplastic transformation inhibitor protein
Supplier: Rockland Immunochemicals
Supplier-Nr: 200-301-B17

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 2E10.C12.H12
Conjugate: No
Host: Mouse
Reactivity: Human (Expected: Mouse, Rat, Xenopus)
Immunogen: synthetic peptide corresponding to residues surrounding Ser457 of the human Pdcd4 protein
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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