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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG66753.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Variant histone H3 which replaces conventional H3 in a wide range of... more
Product information "Anti-phospho-Histone H3 (Ser10), clone SQab20186"
Protein function: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [The UniProt Consortium]
| Keywords: | Anti-phospho-PP781, Anti-phospho-H3.3A, Anti-phospho-H3.3B, Anti-phospho-Histone H3.3 |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG66753 |
Properties
| Application: | IHC (paraffin) |
| Antibody Type: | Monoclonal |
| Clone: | SQab20186 |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Phosphospecific peptide within aa. 1-100 of Human Histone H3. (phosphorylated at Ser10) |
| Format: | Purified |
Database Information
| KEGG ID : | K11253 | Matching products |
| UniProt ID : | P84243 | Matching products |
| Gene ID | GeneID 3020 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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