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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| BR-G01106.100 | 100 µl | - |
7 - 12 business days* |
578.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.... more
Product information "Anti-phospho-H2AX (Ser139) (1H2)"
Protein function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation. [The UniProt Consortium]
| Keywords: | Anti-phospho-H2AX, Anti-phospho-H2a/x, Anti-phospho-H2AFX, Anti-phospho-Histone H2AX, Anti-phospho-Histone H2A.X |
| Supplier: | Bertin Bioreagent |
| Supplier-Nr: | G01106 |
Properties
| Application: | ELISA, WB, ICC |
| Antibody Type: | Monoclonal |
| Clone: | 14HH2-1H2 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | mouse, human |
| Immunogen: | Recombinant TLF protein |
Database Information
| KEGG ID : | K11251 | Matching products |
| UniProt ID : | P16104 | Matching products |
| Gene ID : | GeneID 3014 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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