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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
F4305-02Y.20 | 20 µg | - | - |
3 - 19 business days* |
433.00€
|
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
FGFR1, also known as fibroblast growth factor receptor 1, is a receptor membrane tyrosine kinase... more
Product information "Anti-phospho-FGFR1 (Tyr651/Tyr652) (Basic Fibroblast Growth Factor Receptor 1, bFGF-R-1, CD3"
FGFR1, also known as fibroblast growth factor receptor 1, is a receptor membrane tyrosine kinase belonging to the protein kinase superfamily, Tyr protein kinase family and fibroblast growth factor receptor subfamily with three Ig-like C2-type (immunoglobulin-like) domains and a protein kinase domain. This enzyme acts as a receptor for basic fibroblast growth factor while a shorter form of the receptor could be a receptor for FGF1 (aFGF). Binding of FGFR1 is reported to play a role in the modulation of bone elongation and also in bone development and maintenance. It also mediates two independent signaling pathways in retinal pigment epithelial cells and regulates proliferation, differentiation, and maintenance of normal myocardium. Defects in FGFR1 are responsible for several diseases which include Pfeiffer syndrome (PS), idiopathic hypogonadotropic hypogonadism (IHH), Kallmann syndrome type 2 (KAL2), osteoglophonic dysplasia (OGD), non-syndromic trigonocephaly and many more diseases. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 0.1-1ug/ml, Immunohistochemistry (formalin fixed paraffin embedded): 5ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | EC=2.7.10.1, Anti-phospho-N-sam, Anti-phospho-FLT-2, Anti-phospho-BFGFR, Anti-phospho-Fms-like tyrosine kinase 2, Anti-phospho-Fibroblast growth factor receptor 1, Anti-phospho-Basic fibroblast growth factor receptor 1 |
Supplier: | United States Biological |
Supplier-Nr: | F4305-02Y |
Properties
Application: | IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | bovine, horse, human, mouse, swine |
Immunogen: | Synthetic peptide corresponding to human FGFR1 protein containing phosphorylated tyrosine residues at positions 651 and 652. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K04362 | Matching products |
UniProt ID : | P11362 | Matching products |
Gene ID | GeneID 2260 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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