Anti-phospho-Cofilin 1 (Tyr139)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG51808.50	50 µl		-	-	6 - 14 business days*		436.00€
ARG51808.100	100 µl		-	-	6 - 14 business days*		624.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity.... more

Close menu

Product information "Anti-phospho-Cofilin 1 (Tyr139)"

Protein function: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration. [The UniProt Consortium]

Keywords:	Anti-phospho-p18, Anti-phospho-CFL, Anti-phospho-CFL1, Anti-phospho-Cofilin-1, Anti-phospho-18 kDa phosphoprotein, Anti-phospho-Cofilin, non-muscle isoform
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG51808

Properties

Application:	IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Peptide sequence around phosphorylation site of tyrosine 139 (N-C-Y(p)-E-E) derived from Human cofilin
Format:	Affinity Purified