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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2069-51A.10 | 10 blots | - | - |
3 - 19 business days* |
909.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
b-catenin (92kD) is a multifunctional protein involved in cell-cell adhesion,... more
Product information "Anti-phospho-Catenin, beta (Ser45)"
b-catenin (92kD) is a multifunctional protein involved in cell-cell adhesion, intracellular, signaling and gene transcription. b-catenin plays a key role in the Wnt pathway which mediates numerous developmental processes. Deregulation of the Wnt pathway results in the accumulation of b-catenin in the nucleus. Stabilizing mutations of several serine/threonine residues (more frequently of serine 45) have been found in multiple tumors. Phosphorylation of b-catenin on serine 45 by casein kinase I (CKI) primes its subsequent phosphorylation of residues 33, 37 and 41 by glycogen synthase-3b (GSK-3b) and results in its degradation. Applications: Suitable for use in ELISA and Western Blotting. Other applications not tested. Recommended Dilution: Western Blotting: 1:1000-1:2000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: | United States Biological |
Supplier-Nr: | C2069-51A |
Properties
Application: | ELISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | Synthetic phosphopeptide derived from a region of human b-catenin contains serine 45. Species sequence homology: mouse, rat andfrog. |
Purity: | Purified by immunoaffinity chromatography. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K02105 | Matching products |
UniProt ID : | P35222 | Matching products |
Gene ID | GeneID 1499 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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