Anti-phospho-CaMKII (Thr286) (HRP), clone 22B1

Anti-phospho-CaMKII (Thr286) (HRP), clone 22B1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG24137.50 50 µg - -

6 - 14 business days*

600.00€
 
Protein function: Calcium/calmodulin-dependent protein kinase that functions autonomously after... more
Product information "Anti-phospho-CaMKII (Thr286) (HRP), clone 22B1"
Protein function: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (PubMed:15312654). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity. Acts as a negative regulator of 2-arachidonoylglycerol (2-AG)-mediated synaptic signaling via modulation of DAGLA activity. [The UniProt Consortium]
Keywords: Anti-phospho-Camk2a, Anti-phospho-CaMK-II subunit alpha, Anti-phospho-CaMK-II subunit alpha, Anti-phospho-CaM kinase II subunit alpha, Anti-phospho-CaM kinase II subunit alpha, Anti-phospho-Calcium/calmodulin-dependent protein kinase type II subunit alpha
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG24137

Properties

Application: ELISA, ICC, IF, Immunohistochemistry, IP, WB
Antibody Type: Monoclonal
Clone: 22B1
Conjugate: HRP
Host: Mouse
Species reactivity: human, mouse, rat
Immunogen: Phosphospecific peptide around Thr286 of Rat CaMKII (NP_037052.1)
MW: 54 kD
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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