Anti-phospho-CaMKII (Thr286)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG52238.50	50 µl		-	-	6 - 14 business days*		592.00€

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Protein function: Calcium/calmodulin-dependent protein kinase that functions autonomously after... more

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Product information "Anti-phospho-CaMKII (Thr286)"

Protein function: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission (PubMed:15312654). Regulates dendritic spine development. Also regulates the migration of developing neurons. Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity. [The UniProt Consortium]

Keywords:	Anti-phospho-Camk2a, Anti-phospho-CaMK-II subunit alpha, Anti-phospho-CaM kinase II subunit alpha, Anti-phospho-Calcium/calmodulin-dependent protein kinase type II subunit alpha
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG52238

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	rat (Expected: human, mouse, Xenopus laevis)
Immunogen:	Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr286 conjugated to KLH
MW:	54 kD
Format:	Affinity Purified