Anti-phospho-Caldesmon (Ser789)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG66533.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Actin- and myosin-binding protein implicated in the regulation of actomyosin... more

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Product information "Anti-phospho-Caldesmon (Ser789)"

Protein function: Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also play an essential role during cellular mitosis and receptor capping. Involved in Schwann cell migration during peripheral nerve regeneration. [The UniProt Consortium]

Keywords:	Anti-phospho-CAD, Anti-phospho-CDM, Anti-phospho-CALD1, Anti-phospho-Caldesmon
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66533

Properties

Application:	ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat)
Immunogen:	KLH-conjugated phosphospecific peptide around Ser789 of Human Caldesmon
MW:	93 kD
Format:	Antigen Affinity Purified