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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES5632.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES5632.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by... more
Product information "Anti-phospho-C3G (Tyr504)"
This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008], Protein function: Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1 (PubMed:12432078). Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth. [The UniProt Consortium] Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.. Cellular localization: Early endosome .
Keywords: | Anti-phospho-GRF2, Anti-phospho-RAPGEF1, Anti-phospho-Protein C3G, Anti-phospho-CRK SH3-binding GNRP, Anti-phospho-Guanine nucleotide-releasing factor 2, Anti-phospho-Rap guanine nucleotide exchange factor 1, C3G (phospho Tyr504) rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES5632 |
Properties
Application: | WB, IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse, |
Immunogen: | The antiserum was produced against synthesized peptide derived from human RapGEF1 around the phosphorylation site of Tyr504. AA range:470-519 |
MW: | 120 kD |
Format: | Antiserum |
Database Information
KEGG ID : | K06277 | Matching products |
UniProt ID : | Q13905 | Matching products |
Gene ID | GeneID 2889 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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