Anti-phospho-ATF2 (Ser490/Ser498)

Anti-phospho-ATF2 (Ser490/Ser498)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
609-401-D11 100 µl - -

6 - 10 business days*

684.00€
 
Anti-ATF2 pS490/pS498 Antibody is directed against ATF2 protein phosphorylated at S490/pS498. The... more
Product information "Anti-phospho-ATF2 (Ser490/Ser498)"
Anti-ATF2 pS490/pS498 Antibody is directed against ATF2 protein phosphorylated at S490/pS498. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to remove any unwanted reactivities. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Rabbit Serum. This antibody is specific for phosphorylated ATF2. Minimal reactivity occurs against non-phosphorylated ATF2. Reactivity against ATF2 occurs from human sources. However, reactivity is also expected against rat based on 100% sequence homology. Protein function: Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'- GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2/JUN complex. [The UniProt Consortium]
Keywords: Anti-phospho-HB16, Anti-phospho-ATF2, Anti-phospho-CREB2, Anti-phospho-CREB-2, Anti-phospho-Activating transcription factor 2, Anti-phospho-cAMP-responsive element-binding protein 2, Anti-phospho-cAMP-dependent transcription factor ATF-2
Supplier: Rockland Immunochemicals
Supplier-Nr: 609-401-D11

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: synthetic phospho-peptide corresponding to amino acid residues surrounding Ser490/498.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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