Anti-MEK1/2 (Phospho-Ser218,222)

MAP kinase kinase 1 (MEK1) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase.Synonyms: MAP Kinase Kinase 1/2, MAPKK1/2, Mitogen-activated Protein Kinase Kinase 1/2. Immunogen: phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser218,222 of human MEK1/2. Formulation: (Request formulation change), Affinity-purified IgG. Host: Rabbit. Applications: WB. Origin: Animal/Rabbit.