PTM-Specific Antibodies

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-Nucleophosmin (Ser125) antibody detects Nucleophosmin when phosphorylated at serine 125, encoded by the NPM1 gene. Nucleophosmin is a multifunctional phosphoprotein that shuttles between the...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-JAK1 (Tyr1034/1035) antibody detects Janus kinase 1 phosphorylated at tyrosine residues 1034 and 1035, encoded by the JAK1 gene. Janus kinase 1 is a non-receptor tyrosine kinase that plays an...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-Beta Arrestin 1 (Ser412) antibody detects Beta arrestin 1 phosphorylated at serine 412, encoded by the ARRB1 gene. Beta arrestin 1 is a multifunctional adaptor protein best known for its role...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-VASP (Ser156) antibody is designed to recognize vasodilator-stimulated phosphoprotein (VASP) when phosphorylated at the serine 156 residue. VASP is a member of the Ena/VASP protein family,...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-AMPA Receptor 1 (Ser831) antibody detects AMPA receptor subunit GluA1 when phosphorylated at serine 831, a modification critical for synaptic plasticity. AMPA receptors are glutamate-gated ion...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-p70 S6 Kinase beta (Ser371) antibody detects the phosphorylated form of ribosomal protein S6 kinase beta-1 (S6K1) at serine 371. S6K1, also called p70S6K, is a serine/threonine kinase activated...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic...

In 1X PBS, pH 7.4, with 0.09% sodium azide. Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-Src (Tyr529) antibody detects Src kinase phosphorylated at tyrosine 529, a regulatory modification that maintains Src in an inactive conformation. Src is a non-receptor tyrosine kinase involved...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-Tau (Ser404) antibody detects tau protein (MAPT) when phosphorylated at serine 404, a modification linked to neurofibrillary tangle formation. Tau is a microtubule-associated protein that...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-RBL2 (Thr986) antibody detects retinoblastoma-like protein 2 phosphorylated at threonine 986, a modification regulating its function in the cell cycle. Also known as p130, RBL2 belongs to the...

Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. Phospho-Histone H3 (Ser10) antibody detects histone H3 phosphorylated at serine 10, a key post-translational modification regulating chromatin structure and transcription. Histone H3, encoded by...