MKI67 (human) Antibody Pair

MKI67 (human) Antibody Pair
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABS-ES-181.50 1 set (100 µg & 100 µg) - -

Request delivery time estimate

1,080.00€
 
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm... more
Product information "MKI67 (human) Antibody Pair"
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility (PubMed:27362226). Binds DNA, with a preference for supercoiled DNA and AT-rich DNA (PubMed:10878551). Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization (PubMed:24867636). It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable). [The UniProt Consortium]
Keywords: Anti-Antigen Ki67, Anti-Antigen KI-67, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by monoclonal antibody Ki-67
Supplier: Absea
Supplier-Nr: ES-181

Properties

Application: ELISA
Antibody Type: Mixed
Conjugate: No
Host: Mouse/Mouse
Species reactivity: human
Purity: >85%
Format: Solution

Handling & Safety

Storage: -20°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow. more
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "MKI67 (human) Antibody Pair"
Write a review
or to review a product.
Viewed