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iFluor(TM) 450 Anti-human CD161 Antibody *HP-3G10*

AAT Bioquest
iFluor(TM) 450 Anti-human CD161 Antibody *HP-3G10*
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABD-11610040 100 tests -

3 - 8 business days*

426.00€
ABD-11610041 500 tests -

3 - 8 business days*

1,592.00€
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
 
Description Product Citations Certificate of Analysis Reviews 0
Description
Protein function: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation... more
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Product information "iFluor(TM) 450 Anti-human CD161 Antibody *HP-3G10*"
Protein function: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N- acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as a ligand and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells. [The UniProt Consortium]
Keywords: Anti-CD161, Anti-KLRB1, Anti-CLEC5B, Anti-NKR-P1A, Anti-HNKR-P1a, Anti-C-type lectin domain family 5 member B, Anti-Natural killer cell surface protein P1A, Anti-Killer cell lectin-like receptor subfamily B member 1
Supplier: AAT Bioquest
Supplier-Nr: 1161004

Properties

Application: FC, IF
Antibody Type: Monoclonal
Clone: HP-3G10
Conjugate: iFluor 450
Host: Mouse
Species reactivity: human
Format: Affinity Purified

Database Information

KEGG ID : K06543 | Matching products
UniProt ID : Q12918 | Matching products
Gene ID : GeneID 3820 | Matching products

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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